Publications

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Ipatasertib / Cancer

02/18/2011

Bioorganic & Medicinal Chemistry Letters

Discovery and SAR of spirochromane Akt inhibitors

N. C. Kallan, et al.

ARRY-380 / Breast Cancer

12/10/2010

San Antonio Breast Cancer Symposium

Data from a Completed Phase 1 Study to Assess the Safety, Tolerability and PK of ARRY-380 - an Oral Inhibitor of HER2

S. L. Moulder, et al.

Filanesib / Multiple Myeloma

12/05/2010

American Society of Hematology Annual Meeting

A Phase 1/2 Trial of the KSP Inhibitor ARRY-520 in Relapsed/Refractory Multiple Myeloma

J.J. Shah, MD, et al.

Binimetinib / Cancer

11/16/2010

AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics

MEK162 (ARRY-162), a Novel MEK 1/2 Inhibitor, Inhibits Tumor Growth Regardless of KRas/Raf Pathway Mutations

S. L. Winski, et al.

GDC-0575 / Cancer

10/21/2010

Annual Cancer Targets & Therapeutics Conference

Targeting Checkpoint Kinase 1: A study in the application of preclinical data to inform clinical strategy

M. J. Humphries, et al.

ARRY-380 / Breast Cancer

10/01/2010

American Society of Clinical Oncolog Breast Cancer Symposium

A Phase 1 Study to Assess the Safety, Tolerability and PK of ARRY-380 - an Oral Inhibitor of HER2

PK Morrow, et al.

ARRY-502 / Asthma

09/28/2010

Inflammation Research Association International Conference

Safety, PK and PD of ARRY-502, a CRTh2 Antagonist, in Healthy Subjects with a History of Seasonal Allergies

L. Burgess, et al.

Ipatasertib / Cancer

09/23/2010

PLoS ONE

Crystal Structure of Human AKT1 with an Allosteric Inhibitor Reveals a New Mode of Kinase Inhibition

W. Wu, et al.

ARRY-502 / Asthma

09/21/2010

European Respiratory Society Annual Congress

Safety, PK and PD of ARRY-502, a CRTh2 Antagonist, in Healthy Subjects with a History of Seasonal Allergies

S. Bell, et al.

Ipatasertib / Cancer

08/13/2010

Bioorganic & Medicinal Chemistry Letters

Discovery of pyrrolopyrimidine inhibitors of Akt

James F. Blake, et al.