Publications

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ARRY-380 / Breast Cancer

10/17/2012

American Association of Pharmaceutical Scientists, Annual Meeting and Exposition

Solid-State Characterization of Seven Isomorphic Solvates of ARRY-380

C. Lindemann, et al.

Ipatasertib / Cancer

10/14/2012

International Society for the Study of Xenobiotics North American Regional Meeting

Preclinical ADME Evaluation of GDC-0068, a Novel, ATP-competitive Akt Inhibitor

B. M. Liederer, et al

Ipatasertib / Cancer

09/28/2012

European Society for Medical Oncology Congress

Phase Ib Dose Escalation Study of the Akt Inhibitor GDC-0068 with Docetaxel or mFOLFOX6 in Patients with Advanced Solid Tumors

J.C. Bendell, et al.

Ipatasertib / Cancer

08/30/2012

Journal of Medicinal Chemistry

Discovery and Preclinical Pharmacology of a Selective ATP-Competitive Akt Inhibitor (GDC-0068) for the Treatment of Human Tumors

J. F. Blake, et al.

TrkA

08/29/2012

International Association for the Study of Pain World Congress on Pain

Allosteric Small Molecule Inhibitors of the NGF/TrkA Pathway, A New Approach to Treating Inflammatory Pain

S. W. Andrews, Ph.D.

TrkA

08/28/2012

International Association for the Study of Pain World Congress on Pain

Oral Selective Small Molecule Inhibitors of the TrkA Receptor are Disease Modifying and Provide Pain Relief in a Rat Rheumatoid Arthritis Model

K. S. Bouhana, et al.

TrkA

08/28/2012

International Association for the Study of Pain World Congress on Pain

Potent and Selective, Oral Small Molecule Inhibitors of Tropomyosin-Related Receptor Kinase A (TrkA) for the Treatment of Pain

A. Gomez, et al.

Ipatasertib / Cancer

07/18/2012

Organic Reactions and Processes, Gordon Research Conference

Route Scouting and Early Process Development of a Challenging Cyclopentylpyrimidine Intermediate in ARRY-452/GDC-0068

J. Lane, et al.

ARRY-797 / LMNA DCM

07/05/2012

Human Molecular Genetics

Abnormal p38 mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation

A. Muchir, et al.

ARRY-614 / MDS

06/16/2012

European Hematology Association Annual Congress

Clinical Evaluation of ARRY-614, a Dual p38/Tie2 Inhibitor for Patients with Myelodysplastic Syndromes, Identifies Unique Disease-Related and Drug-Related Biomarkers

G. Garcia-Manero, et al.